منابع مشابه
Merkel Cells Are a Touchy Subject
How the Merkel cell-neurite complex transduces and encodes touch remains unclear. Ikeda et al. now implicate Merkel cells as the primary sites of tactile transduction and the ion channel Piezo2 as the chief mechanotransducer. Surprisingly, Merkel cells also mediate allodynia, providing a new cellular target for chronic pain treatment.
متن کاملA touchy subject: an assessment of cutaneous allodynia in a chronic migraine population
BACKGROUND Cutaneous allodynia (CA) is a common feature of migraine, which has a complex underlying pathophysiology that is not well understood. In addition to pain, photophobia, phonophobia, osmophobia, nausea, and vomiting, CA can contribute to the overall disability caused by migraine. The presence of CA can be established via a validated questionnaire. Validated questionnaires and other tes...
متن کاملA Touchy Subject: Can Physicians Improve Value by Discussing Costs and Clinical Benefits With Patients?
Over the last decade, the cost of health care—and cancer care in particular—has risen dramatically [1, 2]. Increasingly, these costs are being passed on to patients in the form of cost sharing, which can have a catastrophic effect on the financial well-being of patients and their families [3, 4]. This “financial toxicity” of cancer treatment has been shown to impact patients’ finances, leading ...
متن کاملA touchy subject: advancing the modulated visual pathways account of altered vision near the hand
A growing body of evidence demonstrates that human vision operates differently in the space near and on the hands; for example, early findings in this literature reported that rapid onsets are detected faster near the hands, and that objects are searched more thoroughly. These and many other effects were attributed to enhanced attention via the recruitment of bimodal visual-tactile neurons repr...
متن کاملTeaching Touchy Transformations
This paper reports on a teaching unit on model development and model transformation. One example model is first developed and considered as the source of various possible transformations. These transformations are explained implicitly afterwards by showing the different target models obtained by the transformations. The source model and the target models each emphasize a particular aspect, and ...
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ژورنال
عنوان ژورنال: Materials Today
سال: 2005
ISSN: 1369-7021
DOI: 10.1016/s1369-7021(05)70915-9